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Tenecteplase component binds to fibrin and thrombus selectively catalyzes the conversion of thrombus associated plasminogen to plasmin, which destroys a fibrin clot basis.In comparison with a natural tissue plasminogen activator, tenecteplase has a higher affinity for fibrin and resistance to inactivate the endogenous plasminogen activator inhibitor I. After administration of tenecteplase observed dose-α2-antiplasmin consumption (plasmin…